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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX6
All Species:
23.94
Human Site:
S94
Identified Species:
43.89
UniProt:
O95947
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95947
NP_004599.2
436
47045
S94
S
L
P
G
V
S
L
S
L
E
N
R
E
L
W
Chimpanzee
Pan troglodytes
XP_523337
436
47083
S94
S
L
P
G
V
S
L
S
L
E
N
R
E
L
W
Rhesus Macaque
Macaca mulatta
XP_001098963
496
53657
S94
S
L
P
G
V
S
L
S
L
E
N
R
E
L
W
Dog
Lupus familis
XP_547068
436
47185
S94
S
L
P
G
V
S
L
S
L
D
N
R
E
L
W
Cat
Felis silvestris
Mouse
Mus musculus
P70327
540
58610
S94
S
L
P
G
V
S
L
S
L
E
N
Q
E
L
W
Rat
Rattus norvegicus
Q5I2P1
517
57726
G195
A
D
E
N
N
G
F
G
S
K
N
T
A
F
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520749
277
31432
Chicken
Gallus gallus
P79779
361
41167
G53
E
M
I
I
T
K
S
G
R
R
M
F
P
Q
C
Frog
Xenopus laevis
Q8AV66
506
56540
K99
L
P
G
N
V
K
M
K
L
E
N
K
E
L
W
Zebra Danio
Brachydanio rerio
P79742
473
53459
K93
M
V
P
F
D
N
H
K
Y
K
W
N
K
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
T331
V
V
D
D
P
K
V
T
L
E
G
K
D
L
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
D102
R
V
K
I
S
G
L
D
K
K
S
Q
Y
F
V
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
T140
A
T
K
D
I
K
V
T
L
E
G
R
E
L
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
81.8
90.1
N.A.
64.4
34.8
N.A.
43.8
35
43
37
N.A.
22.8
N.A.
35.5
30.2
Protein Similarity:
100
99
83.2
92.1
N.A.
67.9
48.5
N.A.
48.3
47.4
54.5
52.8
N.A.
30.7
N.A.
52.5
43.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
0
0
46.6
6.6
N.A.
26.6
N.A.
6.6
40
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
0
6.6
60
33.3
N.A.
60
N.A.
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% C
% Asp:
0
8
8
16
8
0
0
8
0
8
0
0
8
8
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
54
0
0
54
0
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
8
0
16
0
% F
% Gly:
0
0
8
39
0
16
0
16
0
0
16
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
16
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
0
0
31
0
16
8
24
0
16
8
0
0
% K
% Leu:
8
39
0
0
0
0
47
0
62
0
0
0
0
62
0
% L
% Met:
8
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
16
8
8
0
0
0
0
54
8
0
0
0
% N
% Pro:
0
8
47
0
8
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
16
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
8
0
39
0
0
0
% R
% Ser:
39
0
0
0
8
39
8
39
8
0
8
0
0
0
0
% S
% Thr:
0
8
0
0
8
0
0
16
0
0
0
8
0
0
0
% T
% Val:
8
24
0
0
47
0
16
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
62
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _